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Vardenafil (Generic Equivalent of Levitra)

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Sexual activity can put an extra strain on your heart, especially if your heart is already weak from a heart attack or heart disease.

Status Description Enforcement Level Notes
Prescription-Only Requires valid prescription to buy legally Strict Prescribed for erectile dysfunction
Online Purchase Limited to regulated online pharmacies Moderate Must verify pharmacy license
Import Laws Personal import possible but regulated Strict Customs may seize unapproved imports

WHAT SHOULD YOU DISCUSS WITH YOUR DOCTOR BEFORE TAKING VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? Before taking vardenafil hydrochloride orally disintegrating tablets, tell your doctor about all your medical problems, including if you: · Have heart problems such as angina, heart failure, irregular heartbeats, or have had a heart attack. Ask your doctor if it is safe for you to have sexual activity. · Have low blood pressure or have high blood pressure that is not controlled. · Or any family members have a rare heart condition known as prolongation of the QT interval (long QT syndrome). · Have retinitis pigmentosa, a rare genetic (runs in families) eye disease.

· Have ever had severe vision loss, or if you have an eye condition called non-arteritic anterior ischemic optic neuropathy (NAION). · Have a deformed penis shape or Peyronie’s disease.

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Vardenafil hydrochloride orally disintegrating tablets are not for women or children. Vardenafil hydrochloride orally disintegrating tablets must be used only under a doctor’s care. HOW DOES VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS WORK? When a man is sexually stimulated, his body’s normal physical response is to increase blood flow to his penis. Vardenafil hydrochloride orally disintegrating tablets helps increase blood flow to the penis and may help men with ED get and keep an erection satisfactory for sexual activity.

Chapter 2

Once a man has completed sexual activity, blood flow to his penis decreases, and his erection goes away. WHO CAN TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? Talk to your doctor to decide if vardenafil hydrochloride orally disintegrating tablets are right for you. Vardenafil hydrochloride orally disintegrating tablets have been shown to be effective in men over the age of 18 years who have erectile dysfunction, including men with diabetes. WHO SHOULD NOT TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? · Have had an erection that lasted more bayer vardenafil than 4 hours. · Have blood cell problems such as sickle cell anemia, multiple myeloma, or leukemia. CAN OTHER MEDICATIONS AFFECT VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.

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Vardenafil hydrochloride orally disintegrating tablets and other medicines may affect each other. Always check with your doctor before starting or stopping any medicines. Especially tell your doctor if you take any of the following: · Medicines called nitrates (see “What important information should you know about vardenafil hydrochloride orally disintegrating tablets?”). Patients taking these drugs should not use vardenafil hydrochloride orally disintegrating tablets. Patients taking alpha-blockers should not initiate vardenafil therapy with vardenafil hydrochloride orally disintegrating tablets.

Patients taking alpha-blockers who have previously used vardenafil film-coated tablets may switch to vardenafil hydrochloride orally disintegrating tablets at the advice of their healthcare provider. Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients the use of PDE5 inhibitor drugs, including vardenafil hydrochloride orally disintegrating tablets, with alpha-blockers can lower blood pressure significantly leading to fainting. · Patients should contact the prescribing physician if alpha-blockers or other drugs that lower blood pressure are prescribed by another healthcare provider. HOW SHOULD YOU TAKE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS?

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This leaflet does not take the place of talking with your doctor. You and your doctor should talk about vardenafil hydrochloride orally disintegrating tablets when you start taking it and at regular checkups. If you do not understand the information, or have questions, talk with your doctor or pharmacist. WHAT IMPORTANT INFORMATION SHOULD YOU KNOW ABOUT VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? Vardenafil hydrochloride orally disintegrating tablets are not interchangeable with vardenafil film-coated tablets (LEVITRA).

Contradictions and Special Warnings

Vardenafil hydrochloride orally disintegrating tablets can cause your blood pressure to drop suddenly to an unsafe level if it is taken with certain other medicines. With a sudden drop in blood pressure, you could get dizzy, faint, or have a heart attack or stroke. Vardenafil hydrochloride orally disintegrating tablets contain phenylalanine which can be harmful to people who have phenylketonuria. Do not take vardenafil hydrochloride orally disintegrating tablets if you: · Take any medicines called “nitrates” (often used to control chest pain, also known as angina) · Use recreational drugs called “poppers” like amyl nitrate and butyl nitrate. (See “Who Should Not Take Vardenafil Hydrochloride Orally Disintegrating Tablets?”) Tell all your healthcare providers that you take vardenafil hydrochloride orally disintegrating tablets. Take vardenafil hydrochloride orally disintegrating tablets exactly as your doctor prescribes. Vardenafil hydrochloride orally disintegrating tablets comes in 10 mg orally disintegrating tablets.

Brand Name Price Range (CAD) Pharmacy Presence Online Purchase Allowed
Levitra $20 - $40 per tablet Widely available Yes
Staxyn $25 - $50 per tablet Limited pharmacies Yes
Generic Vardenafil $10 - $25 per tablet Available online Yes

The dose is one vardenafil hydrochloride orally disintegrating tablet. Do not take more than one vardenafil hydrochloride orally disintegrating tablet a day. Doses should be taken at least 24 hours apart. · If you have prostate problems or high blood pressure, for which you take medicines called alpha-blockers, sex medicine you should not start treatment for erectile dysfunction with vardenafil hydrochloride orally disintegrating tablets. Your doctor may prescribe a lower dose of vardenafil film-coated tablet. Take 1 vardenafil hydrochloride orally disintegrating tablet about 1 hour (60 min) before sexual activity. Some form of sexual stimulation is needed for an erection to happen with vardenafil hydrochloride orally disintegrating tablets. Vardenafil hydrochloride orally disintegrating tablets may be taken with or without meals. Place on the tongue where it will dissolve rapidly. The tablet should be taken whole and not crushed or split. The tablet should not be taken with liquid. Call your doctor or emergency room immediately if you accidentally took more vardenafil hydrochloride orally disintegrating tablets than prescribed.

Drug Class Interaction Effect Example Drugs Caution Level
Nitrates Severe hypotension Nitroglycerin High
Alpha-blockers Increased risk of hypotension Tamsulosin, Doxazosin Moderate
CYP3A4 Inhibitors Increased Vardenafil levels, side effects Ketoconazole, Ritonavir High

If you receive vardenafil hydrochloride orally disintegrating tablets in a blisterpack, examine the blisterpack before use. Do not use if blisters are torn, broken, or missing. WHAT ARE THE POSSIBLE SIDE EFFECTS OF VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? The most common side effects with vardenafil hydrochloride orally disintegrating tablets are headache, flushing, stuffy or runny nose, indigestion, upset stomach, dizziness, and back pain.

These side effects usually go away after a few hours. Call your doctor if you get a side effect that bothers you or one that will not go away.

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Do not take vardenafil hydrochloride orally disintegrating tablets if you: · Take any medicines called “nitrates” (see “What important information should you know about vardenafil hydrochloride orally disintegrating tablets?”). Nitrates are commonly used to treat angina. Angina is a symptom of heart disease and can cause pain in your chest, jaw, or down your arm. Medicines called nitrates include nitroglycerin that is found in tablets, sprays, ointments, pastes, or patches. Nitrates can also be found in other medicines such as isosorbide dinitrate or isosorbide mononitrate.

Chapter 52

Some recreational drugs called “poppers” also contain nitrates, such as amyl nitrate and butyl nitrate. Do not use vardenafil hydrochloride orally disintegrating tablets if you are using these drugs. Ask your doctor or pharmacist if you are not sure if any of your medicines are nitrates. · Take riociguat, a guanylate cyclase stimulator, a medicine that treats pulmonary arterial hypertension and chronic-throembolic pulmonary hypertension. · Have been told by your healthcare provider to not have sexual activity because of health problems. Vardenafil hydrochloride orally disintegrating tablets may uncommonly cause: · An erection that won’t go away (priapism). If you get an erection that lasts more than 4 hours, get medical help right away. Priapism must be treated as soon as possible or lasting damage can happen to your penis including the inability to have erections.

Storage and Safety Information

If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took vardenafil hydrochloride orally disintegrating tablets. WHAT ARE VARDENAFIL HYDROCHLORIDE ORALLY DISINTEGRATING TABLETS? Vardenafil hydrochloride orally disintegrating tablets are a prescription medicine taken by mouth for the treatment of erectile dysfunction (ED) in men. ED is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection. A man who has trouble getting or keeping an erection should see his doctor for help if the condition bothers him.

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Vardenafil hydrochloride orally disintegrating tablets may help a man with ED get and keep an erection when he is sexually excited. Vardenafil hydrochloride orally disintegrating tablets does not: · Protect a man or his partner from sexually transmitted diseases, including HIV. Speak to your doctor about ways to guard against sexually transmitted diseases. · Serve as a male form of birth control. Vardenafil hydrochloride erectile dysfunction pills over the counter orally disintegrating tablets are only for men with ED. · Color vision changes, such as seeing a blue tinge to objects or having difficulty telling the difference between the colors blue and green. In rare instances, men taking PDE5 inhibitors (oral erectile dysfunction medicines, including vardenafil) reported a sudden decrease or loss of vision in one or both eyes.

It is uncertain whether PDE5 inhibitors directly cause the vision loss.

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